TikTok Doctor Explains Rare 'Water Allergy' in Viral Video

Aquagenic Urticaria: A Rare Allergy Explained June 1st, 2025, saw a TikTok video by Dr. Rubin, MD, go viral. The video, which has already garnered over 11,300 views, tackles the unusual condition of aquagenic urticaria – an allergy to water. The video begins humorously, depicting a woman's exaggerated reaction to drinking water, before Dr. Rubin, a board-certified allergist, steps in to provide a factual explanation. "It's possible to be allergic to water, but not in the way many people think," explains Dr. Rubin. He clarifies that the allergy doesn't involve ingesting water but rather the skin's reaction to contact. The video highlights two cases Dr. Rubin has personally treated, emphasizing the rarity of the condition. He details treatment options, including high doses of antihistamines and immunomodulatory agents such as Omalizumab (Xolair). Dr. Rubin concludes by advising those struggling with similar symptoms to consult an allergist for proper management. The video's blend of humor and medical accuracy has resonated with viewers, prompting discussions about unusual allergies and the importance of seeking specialized medical care.